The bulletin of the Yamaguchi Medical School

Continued by:Medical Science & Innovation
EISSN:2758-5441

Back to Top

The bulletin of the Yamaguchi Medical School Volume 27 Issue 1-2
published_at 1980-06

Pure Red Cell Aplasia and Diphenylhydantoin

Pure Red Cell Aplasia and Diphenylhydantoin
Kaku Kohei
Kawakatsu Sumio
Matsumoto Nobuo
Miwa Shiro
fulltext
329 KB
A020027000104.pdf
Descriptions
DNA synthesis of mouse L cells in vitro was studied by immunofluorescence and immunoperoxidase techniques using anti-BUdR antibody to identify cells which incorporate BUdR. The fraction of fluorescence- or peroxidase-positive cells agreed well with ^3H-thymidine labeling index. In synchronized cell populations, DNA synthesis rate as measured by fluorescence intensity increased from immediately after block and after plateau of a 4-hr period returned to the initial level in 8 hr. At the mid S phase when DNA synthesis rapidly increased, fluorescence intensity of individual cells varied significantly.
Creator Keywords
pure red cell aplasia
diphenylhydantoin