We investigated the duration of cardiovascular as well as neuromuscular effects of succinylcholine in a patient homozygous for silent gene. The patient remained totally apneic for about 30 min, and the train-of-four ratio was 0.82 even at 150 min after succinycholine 1 mg/kg ⅳ. These results may suggest that cardiovascular and neuromuscular effects of succinylcholine are both prolonged in a patient homozyfous for silent gene.
Succinylcholine
Catecholamines
Abnormal Pseudocholinesterase