The bulletin of the Yamaguchi Medical School

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The bulletin of the Yamaguchi Medical School Volume 33 Issue 1
published_at 1986-12

Synergetic Effects of Dopamine and High-Dose Bumetanide in Patients with oliguria

Synergetic Effects of Dopamine and High-Dose Bumetanide in Patients with oliguria
Sari Atsuo
Oshima Shuzo
Miyauchi Yoshitoyo
Ogasahara Hiroko
Yokota Kimio
Yamashita Shigeki
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A020033000107.pdf
Descriptions
The effects of a combination of dopamine and bumetanide were studied in eight patients with oliguria not responsive to conventional treatment. Dopamine was infused at a rate of 3 чg/kg/min and bumetanide was given as a 0.05-0.1 mg/kg bolus everv 2 hours intravenously. Administration continued for 3 to 15 days. Urine output, blood urea nitrogen, serum creatinine, the ratio of urine to plasma osmolarity, free water clearance, and serum electroiytes were measured before, during, and after the administration period. Six of the eight patients responded with an increase in urine output and improvement of the other variables
Creator Keywords
Dopamine
bumetanide
oliguria
synergetic effect