The bulletin of the Yamaguchi Medical School

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EISSN：2758-5441

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The bulletin of the Yamaguchi Medical School Volume 31 Issue 1
published_at 1984-12

α-Fetnprotein Containing Cells in Early Stages during Hepatocarcinogensis in Rats Fed 2－Acetylaminofluorene

α-Fetnprotein Containing Cells in Early Stages during Hepatocarcinogensis in Rats Fed 2－Acetylaminofluorene
Okita Kiwamu
Noda Ken-ichi
Fukumoto Yohei
Kodama Takahiro
Takemoto Tadayoshi
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A020031000108.pdf
About This Article
Descriptions
The localization of AFP in certain cells in early stages during hepatocarcinogenesis in rats fed 2-AAF was revealed using indirect immunofluorescent technique. AFP containing cells appeared only around the portal triads in the 5th week after the commencement of a 2-AAF diet. With the lapse of time, AFP containing cells, which were shown to be hyperbasophilic hepatocytes by H & E stain, formed foci to nodules.
Creator Keywords
α-fetoprotein (AEP)
hyperplastic nodule
oval cell
2-acetylaminofluorene (2AAF)
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