Cytologic Types of Squamous Carcinoma in Situ of the Uterine Cervix

The neoplastic cells from 30 cases of squamous carcinoma in situ of the uterine cervix have been cytologically subdivided into the following types : small type calls, large type cells, third type cells, large non-keratinizing cells, small cancer cells, keratinizing cancer cells, fiber cells and undifferentiated cancer cells. Small type cells, large type cells and third type cells were commonly seen in the cytologic preparations and one of these types comprised the predominant cancer cell in every case. The cases of mixed type with large and small type cells, large and third type cells, and large and keratinizing cancer cells were not common. Knowledge of the significance of such cell types may be helpful in making a correct cytologic diagnosis. Furthermore, investigations along these lines provide future clues as to growth characteristics of squamous carcinoma in situ of the uterine cervix.