1. Two cases of malignant mesenchymoma (so-called sarcoma botryoides), of which one occurred in the cervix of the uterus and the other arised from the soft palate, are reported. The lesions were treated by a combination of surgery and irradiation with marked effect. Both patients are living and free from recurrence of disease up to date. 2. Brief comment on the histogenesis of the neoplasm has been made and confusion about the designation of the tumors of this type has been pointed out.