Comparative Effects of Acetate and Bicarbonate Dialysates on the Hemodynamic and Respiratory States During Continuous Hemodiafiltration in Critically Iｌｌ Patients.

The purpose of this sutudy is to examine the comparative effects of acetate and bicarbonate dialysates on the cardiopulumonary functions during continuous hemo-diafiltration in 8 critically ill patients. They were dialysed with acetate dialysate for initial 24 hours (stage 1), which was exchanged to bicarbonate dialysate for the next 2 hours (stage 2). Thereafter, bicarbonate dialysate was reexchanged to acetate dialysate (stage 3). Hemodynamic and respiratory parameters were estimated in each stage. No significant difference was recognized among the three stage in any parameter. We concluded that acetate and bicarbonate dialysate had similar effects on the cardiopulmonary functions in the critically ill patients.

Continuous hemodiafiltration

Acetate dialysate

Bicarbonate dialysate

Hemodynamic and respiratory states