STUDIES ON BLOOD SPECTRUM : Ⅰ. BLOOD SPECTRUM AS AN TO THE APPRAISAL OF GENERAL CONDITION

Two thousand and threepatients with medical, surgical, gynecological, and other diseases were examined for theconcentration of blood hemoglobin, serum protein, blood sugar and the slbumin to globulin ratio. Connecting lines were drawn in the graph according to the idea of blood spectrum. They were classified into the four groups, N (albumin to globulin ratio was normal), L (hemoglobin was within normal limits, but albumin to globulin ratio was subnormal), Z (both hemoglobin and albumin to globulin ratio were in subnormal range, whereas serum protein was maintained normal) and F (hemoglobin, serum protein and slbumin to globulin ratio were all below the lower limit of normal range) to be compared with the impairment in general condition which was graded as slight, moderate and severe, and the following conclusions were arrived at:-(1)Groups N, L, Z and F approximetely correspond to the healthy or slightly ill, the slightly or moderately ill, the moderately or severely ill, and the severetly ill conditions, respectively.(2)Each of the four groups contained various patterns (a type and its subtypes) which nearly equivalent in clinical implication, but thtere were a few exception: patterns subtype N. and subtype L. equaled the groups L and group N, respectively, as an indicstor of general condition.(3)In interperting the grade od impaurment in the general condition from the pattern of connecting line, a careful consideration must be paid to the degree of deviation of each constituent (hemoglobin, serum protein or albumin to globulin ratio) from its normal rage, construing larger deviation as being related to a more seriously impaired conditiono and vice versa: Contingency coefficient of 0.45 and the rate of hit of 70 per cent were obtained in this way between the connecting line and The clinically assessed general conditions.(4)The rate of hit varied to a certain extent with the difference in the kind of diseases: it was satisfactorily high in the diseases of the liver and biliary tract, the lungs and, the blood and hematopoietic organs, especially in hepatitis, hepatic cancer, cancer of the biliary tract, and pulmonary tuberculosis, although it was relatively low in the diseases of the pancreas and the thyroid gland as well as in the paitients belonging to psychiatry, neurology and otolaryngokogy. Gastroduodenal ulcer, hypertension, entercolitis (including dysentery), cancer of the breast and diabetes mellitus were generally diagnosed by the blood spectrum as the more favorable than by the purely clinical examination