The study was carried out in an attempt to understand the contribution of endogenous catecholamine on head twitches induced by bromocriptine (BRC), a dopamine D -2 recepter agonist, in rats. Intraperitoneal (I.p.) of BRC (1-10 mg/kg) induced head twitches which are prominent at 2.5mg/kg. The pretreatment with α-methyl-p-tyrosine (α-MPT
Bromocriptine
Dopamine D-2 agonist
Head twitches
Noradrenaline synthesis and release