The bulletin of the Yamaguchi Medical School

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EISSN:2758-5441

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The bulletin of the Yamaguchi Medical School Volume 34 Issue 1
published_at 1987-12

Involvement of Central Presynaptic Noradrenergic Neuron Activity in Head Twitches Induced by Bromocriptine in Rats

Involvement of Central Presynaptic Noradrenergic Neuron Activity in Head Twitches Induced by Bromocriptine in Rats
Ushijima Itsuko
Mizuki Yasushi
Hara Takahide
Kishimoto Osamu
Soeda Koichiro
Tsutsumi Chigusa
Yamada Michio
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Descriptions
The study was carried out in an attempt to understand the contribution of endogenous catecholamine on head twitches induced by bromocriptine (BRC), a dopamine D -2 recepter agonist, in rats. Intraperitoneal (I.p.) of BRC (1-10 mg/kg) induced head twitches which are prominent at 2.5mg/kg. The pretreatment with α-methyl-p-tyrosine (α-MPT
Creator Keywords
Bromocriptine
Dopamine D-2 agonist
Head twitches
Noradrenaline synthesis and release