The bacteriological examinations of the otorrhea taken from 96 patients with chronic otitis media are perormed and the following conclusions are obtained. 1. Staphylococcus aureus, staphylococcus epidermidis, pseudomonas aeruginosa and proteus groups are the common pathogenes of the chronic otitis media. 2. Both pseudomonas and proteus groups are often the causes of the mixed infection and are usually non-sensitive to any antibiotics. 3. The drug sensitivity of the pathogenes isolated from otorrhea seems to weaken in the following order