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Permalink : https://petit.lib.yamaguchi-u.ac.jp/4640
山口医学 Volume 41 Issue 6
published_at 1992-12
The addition of Glutathione (YM737) to a Crystalloid Cardioplegia Enhances Myocardial Protection
Glutathione (YM737)添加心停止液の心筋保護効果
Okada Haruhiko
About This Article
Descriptions
We evaluated the effect of glutathione (YM737) as a free radical scavenger, when added to hypothermic ( 4℃ ) crystalloid cardioplegic solution (K^+23mmol/l). Rabbit hearts were preserved for 3 hours in cardioplegic arrest by infusing 20 ml initially, with additional 10 ml boluses administered every 30 minutes. The myocardial temperature was maintained at 10℃. The hearts were reperfused with KHBB 37℃ in a per fusion circuit for 60 minutes. The animals were divided into two groups. In group I (n=6), crystalloid cardioplegic solution was per fused. In group II(n=6), crystalloid cardioplegic solution containing glutathione (YM737
Creator Keywords
グルタチオン
心筋保護
虚血心筋障害
Other Article
PP. 387 - 393
PP. 401 - 407
PP. 419 - 428