The addition of Glutathione (YM737) to a Crystalloid Cardioplegia Enhances Myocardial Protection
山口医学 Volume 41 Issue 6
Page 387-393
published_at 1992-12
Title
Glutathione (YM737)添加心停止液の心筋保護効果
The addition of Glutathione (YM737) to a Crystalloid Cardioplegia Enhances Myocardial Protection
Creators
Okada Haruhiko
Source Identifiers
Creator Keywords
グルタチオン
心筋保護
虚血心筋障害
We evaluated the effect of glutathione (YM737) as a free radical scavenger, when added to hypothermic ( 4℃ ) crystalloid cardioplegic solution (K^+23mmol/l). Rabbit hearts were preserved for 3 hours in cardioplegic arrest by infusing 20 ml initially, with additional 10 ml boluses administered every 30 minutes. The myocardial temperature was maintained at 10℃. The hearts were reperfused with KHBB 37℃ in a per fusion circuit for 60 minutes. The animals were divided into two groups. In group I (n=6), crystalloid cardioplegic solution was per fused. In group II(n=6), crystalloid cardioplegic solution containing glutathione (YM737
Languages
jpn
Resource Type
journal article
Publishers
山口大学医学会
Date Issued
1992-12
File Version
Not Applicable (or Unknown)
Access Rights
metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools
医学部