Dermatological Findings and Lipid Levels of the Yusho from 1968 to 1982

Total number of the Yusho patients was 44 by the end of 1982. Dermatological symptoms and serum lipid levels of patients were determined at least once a year for 14 years from the onset of poisoning in 1968. The dermatological symptoms 60% of the patients gradually improved until, by 1979, they were nearly indistinguishable while the other 40% of the patients retained comedo and pigmentation. Serum TG and TC levels of 70-80% of the patients decreased gradually, while in the other 20-30% of the patients the levels remained elevated. It was not clear whether or not there was a close correlation between the dermatological symptoms and hyperlipidemia.