Dermatological and laboratory examinations on 17 patients (8 males and 9 females) with chronic Chlorobiphenyls poisoning revealed the following : Main dermatological findings were acne-like eruptions, comedo and darkbrownish pigmented skin, nails and gingiva. Blood chemical analyses revealed hypoalbuminemia, hypertriglyceridemia and anemia. Electrophoresis of lipoprotein of the sera showed hyper pre-β lipoproteins.