We report a case of cholelithiasis which had serious complications after endoscopic sphincterotomy (EST). An 82-year-old male was admitted to our institution for the treatment of obstructive jaundice resulted from choledocholithiasis. He had carried a history of partial gastrectorr.y for early gastric cancer (II a) and reconstruction of the gastrointestinal tract by Billroth I. Soon after admission, EST was performed