山口医学

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山口医学 Volume 42 Issue 1
published_at 1993-02

Therapautic Effects of Thromboxane A_2 Inhibitor for Complete Hepatic Ischemia in Rats

ラット全肝虚血に対するThromboxane A_2 inhibitor(OKYー046)の効果
Kobayashi Tetsuro
Descriptions
The aim of this study was to determine the effects of OKY-046, a thromboxane A_2 inhibitor, on the hepatic dysfunction produced in rats by liver cell ischemia, reperfusion injury or intestinal congestion. Warm total ischemia of the liver was induced by Pringle's method over a 45 minute period. Animals were divided into two groups according to the administration of OKY-046
Creator Keywords
肝虚血
Prostaglandin
Thromboxare A_2 inhibitor
ATP
Mitochondrial score