The aim of this study was to determine the effects of OKY-046, a thromboxane A_2 inhibitor, on the hepatic dysfunction produced in rats by liver cell ischemia, reperfusion injury or intestinal congestion. Warm total ischemia of the liver was induced by Pringle's method over a 45 minute period. Animals were divided into two groups according to the administration of OKY-046
肝虚血
Prostaglandin
Thromboxare A_2 inhibitor
ATP
Mitochondrial score