山口医学

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山口医学 Volume 41 Issue 5
published_at 1992-10

Regulating Roles of Central Inhibitory Systems to Development of Tolerance Induced by Chronic Haloperidol

Haloperidol反復投与によって生じる中枢ドーパミン神経系の耐性現象に対する抑制性神経機構の関与について
Ukita Takeshi
About This Article
Descriptions
The chronic treatment with haloperidol (lmg/kg s.c.) once daily for 21 days reduced the catalepsy induced by haloperidol (0.5mg/kg i.p.) as compared to the chronic saline treated rats (control). The inhibitory effects were reversed by muscimol (lmg/kg
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