山口医学

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山口医学 Volume 35 Issue 1
published_at 1986-02

Dyslipoproteinemia in Renal Failure : Second Report Experimental Study

腎不全におけるリポ蛋白質異常 : 第2報 実験的研究
Takagi Hiromitsu
Descriptions
Using the method of ultracentrifugation and polyacrylamide gel electrophoresis, serum lipoprotein was analyzed in 8 uremic rabbits with increased serum creatinine, serum triglyceride and total cholesterol. In polyacrylamide gel electrophoresis, all 8 rabbits had a wide and dense midband lipoprotein between the beta and pre-beta lipoprotein, which was consistent with the density of 1.006-1.063 in ultracentrifugation. These results suggest that the midband lipoprotein is the subfraction of low density lipoprotein in ultracentrifugation and appeared in the uremic rabbits.