山口医学

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山口医学 Volume 68 Issue 1
published_at 2019-03-01

Jejunal gastrointestinal stromal tumor(gist) : A report of four cases

空腸Gastrointestinal stromal tumor(GIST)の4症例
Nakamura Takashi
Sakano Hisashi
Kudo Junichi
Matsumoto Masaharu
Nakamura Munetaka
Yoneshiro Shigeru
Kuga Takayuki
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B030068000105.pdf
Descriptions
2006年8月から2018年10月までに当院で経験した4例の空腸Gastrointestinal Stromal Tumor(GIST)はすべて女性で,75歳以上が3例,60歳代が1例であった.3例は術前臨床症状がなく,1例は貧血を主訴とした.術前造影Computed Tomography(CT)を行った後に手術を施行した.手術病理標本の免疫組織化学染色上,全例KIT陽性でありGISTと診断した.Fletcher分類で,低リスク3例,中間リスク1例であったため,全例に術後補助療法を行わなかった.3例は生存中で,1例は他病死した.
We encountered four female patients with jejunal gastrointestinal stromal tumor(GIST)between August 2006 and October 2018, of whom three were aged 75 years or older and one was in her 60s. Three patients had no clinical symptoms before surgery and one presented with anemia as a chief complaint. Preoperative contrast-enhanced computed tomography was performed before each surgery. Immunohistochemical examination of the surgical pathology specimens revealed that all cases were positive for KIT, thereby confirming the diagnosis of GIST. According to Fletcher’s classification, three cases were categorized as being low risk and one as intermediate risk. Therefore, no patient required postoperative adjuvant therapy. Three patients are currently alive and one died of intercurrent disease.
Creator Keywords
空腸GIST
高齢患者 
リスク分類 
補助療法