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Permalink : https://petit.lib.yamaguchi-u.ac.jp/24481
山口医学 Volume 63 Issue 4
published_at 2014-11-01
半導体マイクロチップ対応次世代シーケンサーを用いたがん関連遺伝子の解析 (テクニカルノート)
半導体マイクロチップ対応次世代シーケンサーを用いたがん関連遺伝子の解析 (テクニカルノート)
About This Article
Descriptions
半導体マイクロチップ技術を利用した次世代DNAシーケンサーは,比較的長いリード長や迅速な解析等の利点から急速に普及しつつある.また,がんなどの疾患を標的としたアンプリコンライブラリー作製技術も進展し,両者を組み合わせた大規模変異遺伝子解析がより身近なものになった.現在我々の研究室で行っている解析を例に,臨床サンプルを用いたがん関連遺伝子体細胞変異同定法について紹介する.
Creator Keywords
次世代シーケンサー
がん遺伝子
体細胞変異
Other Article
PP. 257 - 261