Laparoscopic examination was performed in three cases (one male and two females) of Wilson's disease including one case of siblings. As clinical stage progress, hepatic parenchymal damage developed. At the early clinical stage, surface of liver showed yellowish, reflecting of steatosis of hepatocytes. With progressive clinical stage, it changed bluish gray, in consequence of the excessive accumulation of copper in liver. With progressive fibrosis, surface of the liver changed nodular appearence. We propose that laparoscopic findings of the hepatic surface in Wilson's disease is useful for diagnosing, determining clinical stage, and evaluating pharmacologic treatment.
本文データは山口大学医学会の許諾に基づきCiNiiから複製したものである