Progressive Peripheral Neuropathy due to Infiltration of Lymphoma Cells into the Peripheral Nerves and Vessels in a Case of Non-Hodgkin's Malignant Lymphoma

A case of non-Hodgkin's malignant lymphoma with progressive peripheral neuropathy was presented. The biopsy of the sural nerve disclosed the infiltration of lymphoma cells into the nerve bundles, vessels and their surrounding tissues. The results indicated the rare infiltration pattern of lymphoma cells along the peripheral nerve system as well as plugging of vessels as a cause of peripheral neuropathy, although the molecular pathogenesis is unknown.

悪性リンパ腫

抹消神経障害

浸潤

神経

血管