The authors have studied the incidence of brain tumors in Yamaguchi prefecture over a 10-year period between 1986 and 1995. Among 2,212 cases registered, 1,464 primary brain tumors were surveyed. The overall age-adjusted incidence rate was 9.4 per 100,000 population per year. Meningiomas were the most frequent tumors (37.5%), followed by gliomas (22.5%). The highest incidence of glimas and meningiomas was seen in patients between 70 and 79 years of age. The incidence of meningioma and pituitary adenoma increased over the 10 years of the survey, probably due to improvements in diagnostic technology and practice The incidence of germ cell tumors was higher in males (male/female raito: 6.50), whereas meningioma, pituitary adenoma, and schwannoma occurred predominantly in females (male/female raito: 0.33, 0.57, 0.59, respectively).