山口医学

Back to Top

山口医学 Volume 39 Issue 6
published_at 1990-12

Amelioration of delayed neuronal death in the gerbil hippocampus by mild hypothermia

砂ネズミ海馬における一過性脳虚血後の遅発性神経細胞壊死に対する低体温の脳保護効果
Yamashita Katsuhiro
Descriptions
The protective effect of mild hypothemia againt delayed neronal death in sector cornu ammonis 1 (CA1 of the gerbil hippocampus was examined at different body temperatures. Transient forebrain inschmia was induced by occulusion of the bilateral common cartoid arteries for 5 min under halothane anesthsia. The rectal temperature during and 10 min after ischmia was controlled in four separate groups as follows : normothermia group, above 36℃ and below 38℃