山口医学

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山口医学 Volume 38 Issue 6
published_at 1989-12

Effect of calcium blocker nicardipine on cerebral circulation, metabolism and neurologic outcome after complete cerebral

カルシウム拮抗薬の前脳虚血後低灌流・神経学的予後に及ぼす影響
Nagai Ikuo
Descriptions
The present study examined the effects of calcium entry blocker, nicardipine, on cerebral blood flow (CBF), cerebral metabolic rate for oxygen (CMRo_2), and neurologic outcome after 10 min of complete cerebral ischemia in dogs. Ischemia was induced by temporal ligation of the ascending aorta and the venae cavae. Fourteen dogs were used for CBF and CMRo_2 studied