山口医学

Back to Top

山口医学 Volume 38 Issue 6
published_at 1989-12

Analysis of hepatic blood flow by radionucletide angiography

Radionuclide angiography による肝血流動体の解析
Suga Kazuyoshi
Tanaka Nobuyuki
Nakata Taishi
Orihashi Norihiro
Okada Fumiyuki
Matsuo Noboru
Inoue Atsushi
Inoue Takeshi
Shimada Yasunobu
Shinchiyou Kouratou
Descriptions
To define the hepatic arterial and portal venous contribution, ^<99m>Tc-Sn colloid angiography was oerformed in various liver diseases by injecting the usual 185 MBq (5 mCi) dose. A time-activity curave of the right lobe of the liver was analized by a computer. In order to eliminate the influence due to lung, a gamma variant fit was performed on the early portion of the first peak of the liver curve and subtracted from the liver curve. The peak of the left kidney curve was chosen as markerto separate the arterial and portal venous phases. The ratio of portal venous to hepatic blood flow was decreased in the fatty liver compared with the normal liver (P<0.05). And the ratio was proportionally decreased with the progression form choronic hepatitis to liver chirosis. The method is very simple and could be applied prior to the conventional static liver imaging.