The Study about the Function of Bile Epithelium in Secretin Test

The bile epithelium cell was disturbed by 18 hours after administration of ANIT 80mg/kg, and secretin did not show any effects to bile secretion. Secretin test (S-test) was performed to the 10 cases of pancreatic head cancers, and in all of them, bile flow and bicarbonate level in the bile increased. The correlation between S-test and decreasing rate of the serum bilirubin was seen. Moreover, the correlation between the decreasing rate of the serum bilirubin and dilation of the bile duct was seen after PTCD. Therefore, it seemed that S-test might be reflection to the disturbance of the bile epithelium. It will be benefit to estimate the function of the bile epithelium.