Clinical Study on Intravenous Hyperalmientation

From Fevruary 1976 to December 1977, twenty-seven adult patients, who required parenteral nutrition, received intravenous hyperralimentation at Yawatahama General Hospital. Central venous catheters were inserted using the infraclavicular subclavian route so that the tip of the catheter lay in the superior vena cava at the entrance into the right atrium. Each patient received 1300-3034 Cal/day. Non protein calories were provided by gloucose (375-500g/day), using Y-T.E..G. which we prepared as a solution of 31.25% glicose and electrolytes (one unit is 400 ml.), and 10% Intrafat. Protein sources were provided by the crystalline amino acid preparation, 12% Ispol (600-800mi/day). Additional electrolytes and vitamins were given on a daily basis. A ratio of non protein calories per gram of nitrogen was 159-168, and a ratio of water per calory was 1 or slight greater than 1. The results of our intravenous hyperlimentation were effective for all of the patients who could be estimated. In laboratory finding, signficant change were not demonstrated with a few exception. However, complications relating to intravenous hyperlimetation were not so few, which were pneumothorax, spontaneous removal of central venous catheter, subclavian artery puncture, fever, sepsis, hyperglycemia, glycosuria, hyperosmolarity, hypernatremia, hyponatremia, liver damage, zinc deficiency uveitis, and pancytopenia. In this report, we will show and discuss our prescription, and also discuss our chinical results and complications of this study