Conservative surgery to preserve ovarian function in patients with ovarian dysgerminomas. 3 case report

Pure ovarian dysgerminoma, a rare tumor accounts for approximately 2% of all ovarian malignancies. During these 20 years, three patients with pure ovarian dysgerminoma were treated at our institution. All patients underwent initial surgery: unilateral salpingo-oophorectomy alone in 1 patient, unilateral salpingo-oophorectomy followed by the combination of cisplatin, vinblastine, and bleomycin (PVB) in 1 patient, and unilateral salpingo-oophorectomy followed by the combination of bleomycin, etoposide, and cisplatin (BEP) in 1 patient. Three pregnancies have occurred in 1 patient with surgery alone. She had two full-term pregnancies. The other two patients had irregular or absent menses during chemotherapy but regained normal menstrual function promptly after chemotherapy. Median follow-up time was 70 months (range, 29 to 261 months). All patients have remained continuously disease-free with maintenance of normal reproductive function.

未分化胚細胞腫(dysgerminoma)

妊孕能温存

cisplatin, vinblastine, and bleomycin (PVB)

bleomycin, etoposide, and cisplatin (BEP)

本文データは山口大学医学会の許諾に基づきCiNiiから複製したものである