Influence of Chronic Ethanol Treatment in Mice on Seizure Thresholds of Convulsant Drugs
β-Carboline誘導体およびNMDAによる痙攣に対するアルコール反復投与の影響
Kawano Michihide
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Descriptions
Mice undergoing withdrawal after chronic treatment with ethanol exhibited lowered seizure thresholds to β-DMCM, a benzodiazepine inverse agonist and to NMDA, a glutamate receptor agonist, but not to bicuculline, a GABA_A receptor antagonist