Castric syphilis : report of three cases

Case 1: A 36-year-old married femal complaind of of epigastralgia, nausea, and vomitting after meal. Upper GI series revealed irregurarity from the angulus to the antrum of the stomach. Endoscopic examination revealed multiple small erosions and faded irregular spots on the lesser curvature from the mid-body to the antrum of the stomach. Case 2 : A 35-year-old married female complained of severa epigastric dull pain, naused, and vomitting. Upper GI series revealed multiple irregular depressed lesions, but no narrowing of the antrum of the stomach. Endoscopic examination revealed multiple irregular depressed lesions and surrounding edema on the total circle of the antrum of the stomach. Case 3 : A 20-year-old unmarried female complained of severa epigastralgia with nausea and loss of appetite. Upper GI series revaled scattered and small spots of the antrum of the stomach. Endoscopic examination revealed multiple shallow erosions with easy-bleeding tendency on the total circle of the antrum of the stomach. In the examination, these three cases were suspected of malignant lesion (case 1, 3) or acute gastric mucosal lesion (case 2). There was no healing tendency by treatment with H_2 receptor antagonist, and biopsy speciments showed non-specific inflammation on all cases. Consequently, these three cases were diagnoses as gastric syphilis with latent syphilis, because of the strong positive reaction of serological test for syphilis and foregoing observations. As showen by endoscopic follow up study, the gastric lesions of all cases were successfully treated by sntiluetic medication.