A nine years old girl of CALLA positive acute lymphoblastic leukemia was treated by autologous bone marrow transplantation (BMT) at the second remission by using autologous bone marrow cells, which was taken at the first remission and was treated with the monoclonal antibodies against leukemic blasts in vitro. The recovery of reticulocyte and granulocyte after BMT was prompt, but the platelet production was depressed, and the patient died of intraabdominal hemorrhage 28 days after BMT.