山口医学

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山口医学 Volume 31 Issue 6
published_at 1982-12

Etiological and Clinical Studies on Alcohol Induced Liver Injury : (1) Etiological Study on Alcohol Induced Fatty Liver

アルコール性脂肪肝の発生要因と治療に関する研究 : (1)基礎的研究
Miyazaki Masako
Descriptions
To consider the pathogenesis of ethanol-induoed fatty liver from the aspect of the drug-metabolizing system, the amount of cytochrome P-450 and lipid peroxides was measured in the liver tissues of the rats given the ethanol diet mixed with Pantethine (antioxidant). After fed the ethanol diet only for 8 weeks, the rats were fed the ethanol diet mixed with Pantethine for 4 weeks. The rats were divided into 3 groups according to diet as follows