Although an efficiency of microscope has improved recently, no report on the design of the instrument can be found. The fundamental consideration on the problem was attempted by the authors, basing upon the human engineering. Subjects mainly discussed were the design and the place of fluorescent screen, operation panel and others. Human conditions, such as human physique, working posture, kinetic curve, working area and others, were also considered. As a result, the following matters were decided to be pratical use. The height of fluorescent screen was 85 cm and the distance between the center of the screen and operator was 25 cm. The location, shape and size of operation panel were decided to be placed on both sides of fluorescent screen plate with 20X40 cm square and the slope of 30 to 45 degree. The arrangement of dials and switches on the operation panel was decided from the view points of manual frequency and precision, and of the right handed aspect of operations. The authors' proposal was very anxious to be accepted by manufacturers in order to improve the effeciency and to keep the good health condition of operators in the electon microscope laboratory.