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Background The lipid-lowering therapy by statins may stabilize and reduce coronary plaques. We compare the effect of strong or moderate statins on the coronary plaque characteristics by using 64-slice multidetector computed tomography (MDCT). Methods and Results We analyzed 13 subjects with non-calcified coronary plaques(NCP)as determined by MDCT. Pitavastatin(PTV:2mg/day)or pravastatin(PRA:10mg/day)were randomly administered. MDCT were performed at 0, 6 and 12 months after lipid-lowering therapy. In PTV group(n=6),CT density of NCP increased by 35.6 ± 28.8 HU after 6 months(p=0.037)and by 30.6 ± 29.8 HU after 12 months(NS).NCP area was decreased by 35.9 ± 15.2 % after 6 months and by 41.0 ± 16.5 % after 12 months(both P=0.001).In PRA group(n=7),CT density of NCP did not significantly increased after 6 months(NS)and after 12 months(NS).NCP area was not significantly decreased at 6 months(NS),but decreased by 23.1 ± 16.7 % at 12 months(P=0.001). Conclusions Serial CT angiography revealed that the regression of NCP occurs rapidly by strong lipid lowering therapy compared to the moderate statin therapy.

Effectiveness of the use of case studies with a new report format for improving public health nurses’home visiting skills for mental health services

山口医学 Volume 66 Issue 2

Creators : Kanehira Tomomi 　 | Morita Takae Publishers : 山口大学医学会 Date Issued : 2017-05-01

Preparation of cation-exchange membranes from polylsulfone with poly (sodium p-styrenesulfonate) graft chains

Bulletin of the Society of Sea Water Science, Japan Volume 70 Issue 6

Creators : Kakihana Yuriko | Ukai Kouhei | Higa Mitsuru Publishers : 日本海水学会 Date Issued : 2016-12-01

Characterization of cation-exchange membranes prepared from PVA-based block copolymers

Bulletin of the Society of Sea Water Science, Japan Volume 70 Issue 5

Creators : Higa Mitsuru | Mizuno Taiko | Anno Marika Publishers : 日本海水学会 Date Issued : 2016-12-01

DMFC performance of polymer electrolyte membranes prepared from a graft-copolymer consisting of a polysulfone main chain and styrene sulfonic acid side chains

Energies Volume 9 Issue 8

Creators : Endo Nobutaka | Ogawa Yoshiaki | Ukai Kohei | Kakihana Yuriko | Higa Mitsuru Publishers : Molecular Diversity Preservation International Date Issued : 2016-08-19

モンテカルロシミュレーション法を用いたタゾバクタム/ピペラシリン (TAZ/PIPC) の最適投与方法の検討

Creators : 河口義隆 Date Issued : 2017

健診データベースを利用した検査値レベル別基準変化量の推定とその閾値の最適化

Creators : 川野伶緒 Date Issued : 2017

「地域精神保健福祉活動における保健師の家庭訪問スキル」の構造化と効果的な現任教育

Creators : 兼平朋美 Date Issued : 2017

Calreticulinは膵癌幹細胞様細胞に高発現している

Creators : 松隈聰 Date Issued : 2017

Study on rational synthesis and dielectric property of mixed-valence polyoxometalate clusters

Creators : 中村一平 Date Issued : 2017