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school大学院医学系研究科(医学)
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Current status of sentinel lymph node biopsy with CT lymphography for breast cancer
Japanese journal of clinical radiology Volume 57 Issue 12
Creators : 菅 一能 | 山本 滋 | 前田 訓子 | 長島 由紀子 | 為佐 路子 | 井上 由佳 | 岡 正朗 Publishers : 金原出版 Date Issued : 2012-11-10
Creators : 菅 一能 | 松永 尚文 | 梶原 浩司 | 大石 真理子 | 藤岡 裕士 Publishers : 金原出版 Date Issued : 2012-11
Spectrum of CT finding in aortic aneurysm
Japanese journal of clinical radiology Volume 58 Issue 1
Creators : 岡田 宗正 | 松永 尚文 | 中島 好晃 | 國弘 佳枝 Publishers : 金原出版 Date Issued : 2013-01
Creators : 岡田 宗正 | 国弘 佳枝 | 中島 好晃 | 佐野 祐一 | 松永 尚文 Publishers : 金原出版 Date Issued : 2013-01
Creators : Ichihara Teruhisa | Akada K. Junko | Kamei Shuichi | Ohshiro Saemi | Sato Daisuke | Fujimoto Masanori | Kuramitsu Yasuhiro | Nakamura Kazuyuki Publishers : American Chemical Society Date Issued : 2006-09
Creators : Nakano Hiroyuki | Mano Takamitsu | Mishima Katsuaki | Kishi Masami | Horinaga Daijyu | Miyawaki Yuichiro | Mori Yoshihide | Ueyama Yoshiya Publishers : Yamaguchi University School of Medicine Date Issued : 2012
Creators : Yamashiro Yasuhiro | Hattori Yukio | Nitta Takenori | Adhiyanto Chris | Matar Maryam M. | Ferania Mella | Takagi Fumiya Publishers : Yamaguchi University School of Medicine Date Issued : 2012
Melatonin protects oocyte from reactive oxygen species
The bulletin of the Yamaguchi Medical School Volume 59 Issue 3-4
Creators : Tamura Hiroshi | Takasaki Akihisa | Taketani Toshiaki | Tanabe Manabu  | Kizuka Fumie | Lee Lifa | Tamura Isao | Maekawa Ryo | Aasada Hiromi | Yamagata Yoshiaki | Sugino Norihiro Publishers : Yamaguchi University School of Medicine Date Issued : 2012
Creators : Fujita Motoki | Maekawa Tsuyoshi | Todani Masaki | Tsuruta Ryosuke Publishers : Yamaguchi University School of Medicine Date Issued : 2012
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited disease characterized by stress- or exercise- induced ventricular tachycardia, frequently leading to sudden cardiac death. A considerable body of evidence accumulated over recent years suggests that mutation-linked cardiac ryanodine receptor (RyR2) defects cause Ca^2+ leak from sarcoplasmic reticulum, which triggers delayed afterdepolarization and leads to CPVT. However, the underlying mechanism, by which a single mutation in such a large molecule causes drastic effects on the channel function, remains elusive. Here we report that introduction of a human CPVT mutation S2246L into the mouse RyR2 induces aberrant activation of channel gating by forming abnormally tight domain-domain interaction between the S2246L mutable domain and the K201-binding domain. This produces more global conformational change in the RyR2: namely, an aberrant domain unzipping between the N-terminal (a.a. 1–600) domain and the central (a.a. 2000–2500) domain owing to the allosteric conformational coupling mechanism. Pharmacological correction of the defective inter-domain interactions can stop the aberrant Ca^2+ release and lethal arrhythmia. These results provide a new pathogenic mechanism of CPVT and a novel therapeutic strategy against CPVT
Creators : Suetomi Takeshi | Yano Masafumi | Matsuzaki Masanori Publishers : Yamaguchi University School of Medicine Date Issued : 2012
Creators : Hiratsuka Atsushi | Smizu Akihiko | Ueyama Takeshi | Doi Masahiro | Yoshida Masaaki | Fukuda Masakazu | Kato Takayoshi | Fumimoto Tomoko | Matsuzaki Masunori Publishers : 日本心臓ペーシング・電気生理学会 Date Issued : 2011
Nippon storm study design
Journal of arrhythmia Volume 28 Issue 5
Creators : Kurita Takashi | Noda Takashi | Nitta Takashi | Furushima Hiroshi | Shimizu Akihiko | Ohe Tohru | Aizawa Yoshifusa | Chiba Yasutaka Publishers : 日本心臓ペーシング・電気生理学会 Date Issued : 2012-10
Creators : Sugimoto Kazutaka | Ideguchi Makoto | Sadahiro Hirokazu | Yoshikawa Koichi | Goto Hisaharu | Nomura Sadahiro | Fujii Masami | Suzuki Michiyasu Publishers : Springer-Verlag Tokyo Date Issued : 2013-01-11
Trial and development of effective instructional materials for echocardiography
Japanese journal of medical ultrasonics Volume 39 Issue 4
Creators : Suenaga Hiromi | Momose Nagisa | Kobayashi Yuki | Syukuwa Yuko Publishers : 日本超音波医学会 Date Issued : 2012-07-15
Examination of body composition analysis factors influencing brachial-ankle pulse wave velocity in workers
Japanese journal of occupational medicine and traumatology Volume 60 Issue 5
Creators : Hiroshige Keiichi | Toyonga Toshihiro | Hiyoshi Etsuko | Fukuda Rika Publishers : 日本職業・災害医学会 Date Issued : 2012-09
Effectiveness of a trial on improving emergency service by cooperation with general practitioners
Journal of Japanese Society for Emergency Medicine Volume 15 Issue 5
Creators : Amiki Masae | Fukuda Shintaro | Nishimura Nobuko | Tamura Kazue | Hara Tetsuya Publishers : 日本臨床救急医学会 Date Issued : 2012-10
Creators : 荒瀬 靖子 | 小笠原 久美 | 小畑 有理子 | 河村 美幸 | 堤 雅恵 Publishers : 医学書院 Date Issued : 2012-12
Creators : 上田 真寿美 | 齊田 菜穂子 | 堤 雅恵 | 岡野 こずえ | 木下 みゆき | 砂川 公美子 | 亀崎 明子 | 田中 満由美 | 松田 昌子 | 中田 智恵 | 生田 奈美可 Publishers : 日本健康教育学会 Date Issued : 2012
Creators : Mizunaga Yuko | Terai Shuji | Yamamoto Naoki | Uchida Koichi | Yamasaki Takahiro | Nishina Hiroshi | Fujita Yusuke | Shinoda Koh | Hamamoto Yoshihiko | Sakaida Isao Publishers : Pergamon Press | Elsevier Science Date Issued : 2012
Creators : Amakawa Genta | Ikemoto Kenzo | Ito Hideaki | Sasaki Kohsuke Publishers : 日本サイトメトリー学会 Date Issued : 2012-09-25
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