山口県大学共同リポジトリ

A novel mutation in IKBKG gene in a female child with incontinentia pigmenti

The bulletin of the Yamaguchi Medical School Volume 69 Issue 1-2 pp. 21 - 25

published_at 2022-06

Incontinentia pigmenti (IP; OMIM# 308300) is a rare inherited disease caused by a mutation of IKBKG, which is also known as NEMO, located on Xq28. IP patients usually present with abnormalities of skin, eyes, nails and central nervous system. The neurological damege, which occur usually from neonatal through the early infantile period, leads to neulogical complication such as development retardation, motor paralysis and epilepsy. However, there has been little study done concerning the effect of therapy for the neural abnormalities. We have investigated the clinical findings in a female IP case with a novel mutation of IKBKG for six years due to disclosing the neurological prognosis and the immunological features. It is hoped that the present study will contribute to a better management of IP patients.

Creators : Sakata Yasufumi Hirano Reiji Yasudo Hiroki Shimomura Yutaka Takada Hidetoshi Suehiro Yutaka Ohga Shouichi Hasegawa Shunji Publishers : Yamaguchi University School of Medicine

Immunoglobulin-resistant kawasaki disease associated with human parvovirus B19 infection

The bulletin of the Yamaguchi Medical School Volume 65 Issue 1-2 pp. 21 - 25

published_at 2018

Creators : Iida Yasunori Hasegawa Shunji Korenaga Yuno Okada Seigo Suzuki Yasuo Hirano Reiji Ohga Shouichi Publishers : Yamaguchi University School of Medicine

Usability of mite-allergen detecting kit 「Mitey Chechker^[○!R]」 especially for the atopic families

The Journal of child health Volume 71 Issue 5 pp. 773 - 779

published_at 2012-09-30

Creators : Hara Masami Matsubara Tomoyo Hasegawa Shunji Furukawa Susumu Publishers : 日本小児保健協会

Tau protein concentrations in the cerebrospinal fluid of children with acute disseminated encephalomyelitis

Official journal of The Japanese Society of Child Neurology

published_at 2013-01-03

Creators : Oka Momoko Hasegawa Shunji Matsushige Takeshi Inoue Hirofumi Kajimoto Madoka Ishikawa Naoko Isumi Hiroshi Ichiyama Takashi Publishers : The Japanese Society of Child Neurology | Elsevier Science

The examination of the food allergen residual food-allergen on a cooking utensil or a thing of tableware after washing

小児保健研究 Volume 70 Issue 6 pp. 744 - 752

published_at 2011-11

Creators : Hara Masami Hasegawa Shunji Yamaguchi Koichi Katsumata Noriko Yamamoto Misato Furukawa Susumu Publishers : 日本小児保健協会

Intravenous immunoglobulin does not increase FcγRIIB expression levels on monocytes in children with immune thrombocytopenia

Clinical and experimental immunology Volume 169 Issue 1 pp. 33 - 37

published_at 2012-07

Creators : Shimomura M. Hasegawa S. Seki Y. Fukano R. Hotta N. Ichiyama T. Publishers : Blackwell Scientieic

アトピー性皮膚炎患者におけ末梢血NK細胞数の検討

The journal of the Japan Pediatric Society Volume 116 Issue 2 pp. 361 - 361

published_at 2012-02-01

Creators : 長谷川俊史岡田清吾平野玲史市山高志 Publishers : 日本小児科学会

ヒト気道上皮細胞におけるウィルス感染によるサイトカイン産生の検討

Japanese journal of allergology Volume 60 Issue 9 pp. 1437 - 1437

published_at 2011-10-10

Creators : 長谷川俊史岡田清吾橘髙節明平野玲史市山高志 Publishers : 日本アレルギー学会

当科における小児気管支喘息発作入院症例のウイルス学的検討

Japanese journal of allergology Volume 60 Issue 9 pp. 1393 - 1393

published_at 2011-10-10

Creators : 平野玲史長谷川俊史岡田清吾脇口宏之市山高志 Publishers : 日本アレルギー学会

Molecular epidemiological study of human rhinovirus species A, B and C from patients with acute respiratory illnesses in Japan

Journal of medical microbiology Volume 61 Issue 3 pp. 410 - 419

published_at 2012-03

Creators : Arakawa Mika Okamoto-Nakagawa Reiko Toda Shoichi Tsukagoshi Hiroyuki Kobayashi Miho Ryo Akihide Mizuta Katsumi Hasegawa Shunji Hirano Reiji Wakiguchi Hiroyuki Kudo Keiko Tanaka Ryota Morita Yukio Noda Masahiro Kozawa Kunihisa Ichiyama Takashi Shirabe Komei Kimura Hirokazu Publishers : Churchill Livingstone

Leukotriene D_4 enhances tumor necrosis factor-α-induced vascular endothelial growth factor production in human monocytes/macrophages

Cytokine Volume 55 Issue 1 pp. 24 - 28

published_at 2011-07

Creators : Haneda Yasuhiro Hasegawa Shunji Hirano Reiji Hashimoto Kunio Ohsaki Ayami Ichiyama Takashi Publishers : Saunders

Serum and cerebrospinal fluid cytokine profile of patients with 2009 pandemic H1N1 influenza virus-associated encephalopathy

Cytokine Volume 54 Issue 2 pp. 167 - 172

published_at 2011-05

Creators : Hasegawa Shunji Matsushige Takeshi Inoue Hirofumi Shirabe Komei Fukano Reiji Ichiyama Takashi Publishers : Saunders

Cysteine, histidine and glycine exhibit anti-inflammatory effects in human coronary arterial endothelial cells

Clinical and experimental immunology Volume 167 Issue 2 pp. 269 - 274

published_at 2012-02

Creators : Hasegawa S. Ichiyama T. Sonaka I. Ohsaki A. Okada S. Wakiguchi H. Kudo K. Kittaka S. Hara M. Furukawa S. Publishers : Blackwell Scientieic

Enterovirus 68 infection in children with asthma attacks: virus-induced asthma in Japanese children

Allergy Volume 66 Issue 12 pp. 1618 - 1620

published_at 2011-12

Creators : Hasegawa S. Hirano R Okamoto-Nakagawa R. Ichiyama T. Shirabe K. Publishers : Munksgaard

Use of the Rigid Bronchoscope with the Endoscopic Telescope

山口医学 Volume 48 Issue 4 pp. 159 - 164

published_at 1999-08

Creators : Sugahara Kazuma Okinaka Yoshihiko Imate Yuji Shimogori Hiroaki Ogata Yoichi Noguchi Fumiko Fukui Kazuko Yamashita Hiroshi Fujinami Tomoyuki Hasegawa Toshifumi Publishers : 山口大学医学会