山口県大学共同リポジトリ

An invited review following the Soujinkai Fujiu Memorial Award : elucidation of drug resistance mechanisms in prostate cancer: overcome them by investigating bench to bedside

The bulletin of the Yamaguchi Medical School Volume 69 Issue 1-2 pp. 1 - 9

published_at 2022-06

Androgen receptor (AR)-signaling plays an important role in promoting tumor cell survival and the development of castration-resistant prostate cancer (CRPC). Androgen deprivation therapy is the basic therapeutic strategy for AR signaling blockade, but that effects wonʼt last long and most of metastatic prostate cancer show castration resistance. Recently, new agents, AR Axis Targeted agents (ARAT), have been developed. We have been developing our bench-to-bedside translational research to elucidate the mechanisms of drug resistance in prostate cancer. This review describes our investigational results and recent advances in CRPC with ARAT treatment strategy.

Creators : Matsumoto Hiroaki Matsuyama Hideyasu Publishers : Yamaguchi University School of Medicine

Phase II trial of zoledronic acid combined with androgen-deprivation therapy for treatment-naive prostate cancer with bone metastasis

ICCJ Volume 19 Issue 4 pp. 693 - 701

published_at 2014-08

Creators : Nozawa Masahiro Inagaki Takeshi Nagao Kazuhiro Nishioka Tsukasa Komura Takahiro Esa Atsunobu Kitagawa Michiko Imanishi Masaaki Uekado Yasunari Ogawa Takatoshi Kajikawa Hiroshi Uejima Shigeya Matsuyama Hideyasu Hara Isao Uemura Hirotsugu Publishers : 日本癌治療学会

Crosstalk of clusterin expression with androgen receptor signal transduction and its therapeutic target for castration-resistant prostate cancer

西日本泌尿器科 Volume 75 Issue 4 pp. 170 - 177

published_at 2013-04-20

Creators : Matsumoto Hiroaki Matsuyama Hideyasu Publishers : 日本泌尿器科学会西日本総会

Combination of hemoglobin, alkaline phosphatase, and age predicts optimal docetaxel regimen for patients with castration-resistant prostate cancer

International journal of clinical oncology Volume 19 Issue 5 pp. 946 - 954

published_at 2014-10

Creators : Matsuyama Hideyasu Shimabukuro Tomoyuki Hara Isao Kohjimoto Yasuo Suzuki Kazuhiro Koike Hidekazu Uemura Hirotsugu Hayashi Taiji Ueno Munehisa Kodaira Kiichiro Tomita Yoshihiko Sakurai Toshihiko Shimizu Nobuaki Publishers : 日本癌治療学会

Symptomatic polycystic liver disease treated with transcatheter hepatic arterial embolization and inferior vena cava stenting : A case report

official journal of the Middle East Society for Organ Transplantation Volume 12 Issue 4 pp. 377 - 380

published_at 2014-08

Creators : Fujita Takeshi Tanabe Masahiro Uchiyama Koichi Matsuyama Hideyasu Matsunaga Naofumi Publishers : Baskent University

去勢抵抗性前立腺癌と筋層浸潤性膀胱癌を併発した症例に対しGDC療法が奏効した1例

西日本泌尿器科 Volume 75 Issue 1 pp. 22 - 26

published_at 2013-01-20

Creators : Nagata Yudai Hara Takahiko Matsuyama Hideyasu Isoyama Riichirou Publishers : 日本泌尿器科学会西日本総会

Microdissection testicular sperm extraction and salvage hormonal treatment in patients with postchemotherapy azoospermia

Urology Volume 83 Issue 1 pp. 100 - 106

published_at 2014-01

Creators : Shiraishi Koji Matsuyama Hideyasu Publishers : Elsevier

Enhanced diagnostic accuracy for quantitative bone scan using an artificial neural network system : A Japanese multi-center database project

EJNMMI Research Volume 3 Issue 1

published_at 2013

Creators : Nakajima Kenichi Nakajima Yasuo Horikoshi Hiroyuki Ueno Munehisa Wakabayashi Hiroshi Shiga Tohru Yoshimura Mana Ohtake Eiji Sugawara Yoshifumi Matsuyama Hideyasu Edenbrandt Lars Publishers : Springer

Editorial Comment to Role of routine transurethral biopsy and isolated upper tract cytology after intravesical treatment of high-grade non-muscle invasive bladder cancer

International journal of urology Volume 19 Issue 11 pp. 994 - 994

published_at 2012-11-01

Creators : Matsuyama Hideyasu Publishers : Churchill Livingstone Japan | Blackwell Science Asia

Experience of microdissection testicular sperm extraction: Initial 250 cases

Nishinihon Journal of Urology Volume 75 Issue 7 pp. 345 - 351

published_at 2013-07

Creators : 白石晃司西嶋淳松山豪泰 Publishers : 日本泌尿器科学会西日本総会

Urinary bladder metastasis arising from prostate cancer : a case report

Nishinihon Journal of Urology Volume 75 Issue 7 pp. 364 - 368

published_at 2013-07

Creators : 井内俊輔川井禎久白石晃司松山豪泰 Publishers : 日本泌尿器科学会西日本総会

Cotargeting androgen receptor and clusterin delays castrate-resistant prostate cancer progression by inhibiting adaptive stress response and AR stability

Cancer Research Volume 73 Issue 16 pp. 5206 - 5217

published_at 2013-08-15

Creators : Matsumoto H. Yamamoto Y. Shiota M. Kuruma H. Beraldi E. Matsuyama H. Zoubeidi A. Gleave M. Publishers : American Association for Cancer Research

T1/high-grade膀胱癌に対するsecond TURの検討と予後予測の試み

The Nishinihon journal of urology Volume 75 Issue 6 pp. 311 - 317

published_at 2013-06

Creators : 原貴彦小林圭太西嶋淳川井禎久松本洋明長尾一公坂野滋松山豪泰 Publishers : 日本泌尿器科学会西日本連合地方会

Diagnosis system for predicting the centrosome hyperamplification in bladder cancer by using DNA microarray data

Journal of advanced computational intelligence and intelligent informatics Volume 17 Issue 2 pp. 244 - 251

published_at 2013-03

Creators : Tokunaga Kazuhiro Kubosaka Fumiya Suetake Noriaki Uchino Eiji Matsuyama Hideyasu Publishers : Fuji Technology Press

Nocturia potentially influences maintenance of sexual function in elderly men with benign prostatic hyperplasia

Lower urinary tract symptoms Volume 5 Issue 2 pp. 75 - 81

published_at 2013-03

Creators : Ishizuka Osamu Matsuyama Hideyasu Sakai Hideki Matsubara Akio Nagaoka Akira Takahashi Satoru Takeda Masayuki Ozono Seiichiro Shiroki Ryoichi Shuin Taro Hara Isao Kakizaki Hidehiro Tsukamoto Taiji Yamanishi Tomonori Yokoyama Osamu Kakehi Yoshiyuki Nishizawa Osamu Publishers : Blackwell Pub. Asia

Can docetaxel therapy improve overall survival from primary therapy compared with androgen-deprivation therapy alone in Japanese patients with castration-resistant prostate cancer? A multi-institutional cooperative study

International journal of clinical oncology Volume 18 Issue 1 pp. 62 - 67

published_at 2013-02

Creators : Shimabukuro Tomoyuki Sakano Shigeru Matsuda Kenji Kamiryo Yoriaki Yamamoto Norio Kaneda Yoshitaka Nasu Takahito Baba Yoshikazu Suga Akinobu Yamamoto Mitsutaka Aoki Akihiko Takai Kimio Yoshihiro Satoru Konishi Motohiko Imoto Katsuhiko Matsuyama Hideyasu Publishers : Churchill Livingstone | Springer

PDD(photodynamic diagnosis)の有用性とその解決すべき問題点 : 偽陽性の分子生物学的検討 (＜特集1＞光力学診断の新展開 : 光の先に何が見えるのか)

Japanese journal of Endourology Volume 24 Issue 1 pp. 2 - 7

published_at 2011-05-01

Creators : 松山豪泰 Publishers : 日本泌尿器内視鏡学会

Deflux injection therapy for vesicoureteral reflux in a patient with a transplanted kidney: A case report

西日本泌尿器科 Volume 74 Issue 11 pp. 628 - 631

published_at 2012-11

Creators : 廣吉俊弥 Fujikawa Koki Uchiyama Koichi Tsuchida Masahiro Matsuyama Hideyasu Publishers : 日本泌尿器科学会西日本総会

A case of primary chondrosarcoma difficult to differentiate from retroperitoneal tumor

Acta urologica Japonica Volume 58 Issue 11 pp. 605 - 608

published_at 2012-11

Creators : Nagata Yudai Shiraishi Koji Matsuyama Hideyasu Publishers : 京都大学医学部泌尿器科教室

限局性前立腺癌に対する金球マーカー併用強度変調放射線療法(IMRT)の初期治療成績

Japanese journal of urological surgery Volume 25 Issue 8 pp. 1693 - 1695

published_at 2012-08-15

Creators : Matsumoto Hiroaki Nishijima Jun Miyachika Yoshihiro Kawai Yoshihisa Hara Takahiko Sakano Shigeru 沖本智明 Matsunaga Naofumi Matsunga Hideyasu Publishers : 医学図書出版

Comparison of the results and complications of retroperitoneal, microsurgical subinguinal, and high inguinal approaches in the treatment of varicoceles

Journal of andrology Volume 33 Issue 6 pp. 1387 - 1393

published_at 2012-11

Creators : Shiraishi Koji Oka Shintaro Ito Hideaki Matsuyama Hideyasu Publishers : J.B. Lippincott Co. | American Society of Andrology

Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology

International journal of urology Volume 19 Issue 6 pp. 538 - 550

published_at 2012-06

Creators : Shiraishi Koji Matsuyama Hideyasu Takihara Hiroshi Publishers : Churchill Livingstone Japan　社団法人日本泌尿器科学会 | Blackwell Science Asia

Combined functional genome survey of therapeutic targets for clear cell carcinoma of the kidney

Japanese journal of clinical oncology Volume 41 Issue 7 pp. 847 - 853

published_at 2011-07

Creators : Ito Hideaki Honda Kazufumi Satow Reiko Arai Eri Shitashige Miki Ono Masaya Sakuma Tomohiro Sakano Shigeru Naito Katsusuke Matsuyama Hideyasu Yamada Tesshi Publishers : Foundation of Clinical Oncology

Primary cT2 bladder cancer : a good candidate for radiotherapy combined with cisplatin for bladder preservation

Japanese journal of clinical oncology Volume 41 Issue 7 pp. 902 - 907

published_at 2011-07

Creators : Hara Takahiko Nishijima Jun Miyachika Yoshihiro Yamamoto Yoshiaki Sakano Shigeru Matsuyama Hideyasu Publishers : Foundation of Clinical Oncology

Microscopic high inguinal approach for the treatment of varicocele

西日本泌尿器科 Volume 74 Issue 9 pp. 483 - 491

published_at 2012-09

Creators : 白石晃司松山豪泰 Publishers : 日本泌尿器科学会西日本総会

Prognostic significance of preoperative erythrocyte sedimentation rate in localized clear cell renal cell carcinoma

西日本泌尿器科 Volume 74 Issue 9 pp. 492 - 496

published_at 2012-09

Creators : 川井禎久西嶋淳山本義明松本洋明長尾一公原貴彦坂野滋松山豪泰 Publishers : 日本泌尿器科学会西日本総会

Splenectomy protects the kidneys against ischemic reperfusion injury in the rat

Transplant immunology Volume 27 Issue 1 pp. 8 - 11

published_at 2012-08

Creators : Hiroyoshi Toshiya Tsuchida Masahiro Uchiyama Koichi Fujikawa Koki Komatsu Takahiro Kanaoka Yoshihiro Matsuyama Hideyasu Publishers : Edward Arnold | Elsevier Science

TESE時代における内分泌療法の復権

Japanese journal of urological surgery Volume 25 Issue 臨時増刊 pp. 989 - 991

published_at 2012-04-25

Creators : 白石晃司松山豪泰 Publishers : 医学図書出版

DNA copy number aberrations associated with lymphovascular invasion in upper urinary tract urothelial carcinoma

Cancer genetics Volume 205 Issue 6 pp. 313 - 318

published_at 2012-06

Creators : Misumi Taku Yamamoto Yoshiaki Miyachika Yoshihiro Eguchi Satoshi Chochi Yasuyo Nakao Motonao Nagao Kazuhiro Hara Takahiko Sakano Shigeru Furuya Tomoko Oga Atsunori Kawauchi Shigeto Sasaki Kohsuke Matsuyama Hideyasu Publishers : Elsevier

Could basic research shed light on false positivity in photodynamic diagnosis?

International journal of urology Volume 19 Issue 8 pp. 695 - 696

published_at 2012-08

Creators : Matsuyama Hideyasu Publishers : Churchill Livingstone Japan | Blackwell Science Asia

Association of RASSF1A genotype and haplotype with the progression of clear cell renal cell carcinoma in Japanese patients

BJU international Volume 110 Issue 7 pp. 1070 - 1075

published_at 2012-10

Creators : Kawai Yoshihisa Sakano Shigeru Okayama Naoko Suehiro Yutaka Matsuyama Hideyasu Hinoda Yuji Publishers : Blackwell Science

The prognosis of non-muscle invasive bladder cancer

西日本泌尿器科 Volume 73 Issue 10 pp. 538 - 547

published_at 2011-10-20

Creators : Matsuyama Hideyasu Publishers : 日本泌尿器科学会西日本総会

第99回日本泌尿器科学会総会印象記

西日本泌尿器科 Volume 73 Issue 8 pp. 439 -

published_at 2011-08-20

Creators : 松山豪泰 Publishers : 日本泌尿器科学会西日本連合地方会

Diagnosis and grading of urothelial carcinomas by multicolor : FISH in 305 cases of bladder washings

Cytometry research Volume 21 Issue 1 pp. 65 - 70

published_at 2011-03-25

Creators : lkemoto Kenzo Eguchi Satoshi Furuya Tomoko Oga Atsunori Kawauchi Shigeto Matsuyama Hideyasu Sasaki Kohsuke Publishers : 日本サイトメトリー学会

Risk group stratification to predict recurrence after transurethral resection in Japanese patients with stage Ta and T1 bladder tumours: validation study on the European Association of Urology guidelines

BJU international Volume 107 Issue 10 pp. 1598 - 1604

published_at 2011-05

Creators : Sakano Shigeru Matsuyama Hideyasu Takai Kimio Yoshihiro Satoru Kamiryo Yoriaki Shirataki Satoshi Kaneda Yoshitaka Hashimoto Osamu Joko Keiji Suga Akinobu Yamamoto Mitsutaka Hayashida Shigeaki Baba Yoshikazu Aoki Akihiko The Yamaguchi Uro-Oncology Group Publishers : Blackwell Science

Clinical significance of centrosome amplification in bladder cancer

山口医学 Volume 59 Issue 1 pp. 9 - 15

published_at 2010-02-28

Creators : Matsuyama Hideyasu Publishers : 山口大学医学会

Intercellular centrosome number is correlated with the copy number of chromosomes in bladder cancer

Cancer genetics and cytogenetics Volume 191 Issue 1 pp. 38 - 42

published_at 2009-05

Creators : Yamamoto Yoshiaki Eguchi Satoshi Akao Junpei Nagao Kazuhiro Sakano Shigeru Furuya Tomoko Oga Atunori Kawauchi Shigeto Sasaki Kohsuke Matsuyama Hideyasu Publishers : Elsevier

Genetic and epigenetic analysis on urological malignancies using molecular biological techniques

山口医学 Volume 53 Issue 2 pp. 99 - 101

published_at 2004-04-30

Creators : Matsuyama Hideyasu Hirata Hiroshi Yano Seiji Yamamoto Yoshiaki Korenaga Yoshihito Inoue Ryo Hara Tomohiko Ohmi Chietaka Sakano Shigeru Yoshihiro Satoru Publishers : 山口大学医学会

Nuclear p53 overexpression in pathological T1 bladder cancer : a marker for tumor recurrence and tumor progression

The bulletin of the Yamaguchi Medical School Volume 48 Issue 1-2 pp. 7 - 12

published_at 2001-06

Creators : Tsukamoto Manabu Oba Kazuo Yoshihiro Satoru Matsuyama Hideyasu Takahashi Mutsuo Naito Katsusuke Publishers : Yamaguchi University Graduate School of Medicine

Role of alpha-actinin-4 in the regulation of endocytosis

The bulletin of the Yamaguchi Medical School Volume 55 Issue 3-4 pp. 21 - 26

published_at 2008

Creators : Hara Tomohiko Honda Kazufumi Shitashige Miki Ono Masaya Matsuyama Hideyasu Naito Katsusuke Hirohashi Setsuo Yamada Tesshi Publishers : Yamaguchi University School of Medicine

Analysis of genomic alterations on urological malignancies by fluorescence in situ hybridization

The bulletin of the Yamaguchi Medical School Volume 50 Issue 1-4 pp. 11 - 18

published_at 2003-12

Creators : Matsuyama Hideyasu Pan Yi Oba Kazuo Tsukamoto Manabu Nagao Kazuhiro Yamaguchi Shiro Fukunaga Koji Matsuda Kenji Yoshihiro Satoru Li Chunde Kudren David Bergerheim Ulf S. R. Ekman Peter Naito Katsusuke Publishers : Yamaguchi University Graduate School of Medicine

9p21 index as estimated by dual-color fluorescence in situ hybridization is useful to predict urothelial carcinoma recurrence in bladder washing cytology

Human pathology : a clinicopathologic quarterly Volume 40 Issue 12 pp. 1783 - 1789

published_at 2009-12

Creators : Kawauchi Shigeto Sakai Hajime Ikemoto Kenzo Eguchi Satoshi Nakao Motonao Takihara Hirofumi Shimabukuro Tomoyuki Furuya Tomoko Oga Atsunori Matsuyama Hideyasu Takahashi Mutsuo Sasaki Kohsuke Publishers : Elsevier

Colony Formation Assay for In Vitro Chemosensitivity Test of Urologic malignancies

The bulletin of the Yamaguchi Medical School Volume 36 Issue 1-2 pp. 49 - 54

published_at 1989-06

Creators : Yamamoto Norio Matsuyama Hideyasu Sakatoku Jisaburo Publishers : Yamaguchi University Graduate School of Medicine