Serum interleukin -6 responses to the two 400-meter swimming in recreational college swimmers

Purpose: The aim of this study was to investigate the effect of the two 400-m swimming on serum IL -6 levels. Methods: Eight male swimmers completed the two 400-m swimming, at interval of 1 hour, in the free-style stroke. Blood samples were collected before, immediately, and 30 min after swimming, on the first and second swimming, respectively. Results and Discussion: Blood lactate lactic acid concentration elevated to about 4mmol/ 1 after each swimming. After the first swimming, serum 1L-6 increased about l.5-fold, (1.205+0.756 to 1.852+0.603 pg/ml, p <0.05), in the second swimming, serum IL-6 also increased about 1.5-fold, (1.289±0.689 to 1.952± 1.439 pg/ml, NS) .These results suggest that a brief swimming (5 to 6 min) at the exercise intensity to the onset of blood lactate accumulation (4 mmol/l) may increase serum IL-6. 1.5-fold. Although the increase in IL -6 in the circulation depends on several factors including exercise intensity, duration, and mode, the muscle mass involved in the contractile activity, swimming is a whole body exercise, and most of muscle is recruited in the free-style stroke, accordingly, 5 to 6 min of 400-m swimming may increase serum IL-6 1.5-fold.

Interleukin - 6

the onset of lactate accumulationn

400-m swimming