Purpose: There is little information concerning the changes which occur in salivary compositions in response to exercise. Therefore, we investigate that the changes in markers of salivary oxidation-reduction status. Methods: Seven healthy males completed the exercise by bicycle ergo-meter of 70%HR reserve for 30 min. Saliva samples were collected before, immediately after, andl, 6 and 24 h after exercise. Results and Discussion: Although the interaction effect is significant in salivary secretion rate, amylase and lysozyme activities, there were uncertain whether or not the changes in salivary markers are affected by exercise. Salivary ORP gradually decreased alter exercise, and salivary peroxidase (Pox) and uric acid were no changes by exercise. There is a positive correlation between the salivary pH and the peroxidase (r=0.633, p < 0.01), and the uric acid (r=0.559, p < 0.01). Uric acid, uie mosi important antioxidant molecule in saliva, contribute approximately 70% of the total salivary antioxidant capacity, and peroxidase catalyzed the reaction to tne hypothiocynous acid from thiocynate which is the electron-donating component. These results suggest that exercise in this experiment conditions is not affected on the oxidation-reduction status in saliva.