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Body composition as a novel prognostic biomarker for the patients with advanced hepatocellular carcinoma

山口医学 Volume 70 Issue 4

Creators : Saeki Issei Publishers : 山口大学医学会 Date Issued : 2021-12-02

Novel mechanisms regulating myogenic differentiation in skeletal muscle

山口医学 Volume 70 Issue 4

Creators : Honda Takeshi Publishers : 山口大学医学会 Date Issued : 2021-12-02

Decision making support in end-of-life care for patients with non-cancer respiratory disease in Japan : a literature review

山口医学 Volume 70 Issue 3

Creators : Ishikawa Yoshiko | Ito Misae Publishers : 山口大学医学会 Date Issued : 2021-09-01

Safety and influence of molecular hydrogen/carbon dioxide contained drinking water on common anthropometric and laboratory parameters

山口医学 Volume 70 Issue 3

The process of assessment and intervention by nurses in the ＂concerns and true feelings＂ of terminal cancer patients in general wards

山口医学 Volume 70 Issue 3

Creators : Tanaka Aiko | Nagata Chizuru | Goth Miyuki Publishers : 山口大学医学会 Date Issued : 2021-09-01

Liquid biopsy test based on a sensitive dna methylation assay for diagnosing hepatocellular carcinoma : which is a better marker, methylated sst or sept9?

山口医学 Volume 70 Issue 3

We performed this study to investigate whether serum cell-free DNA testing(liquid biopsy)of either methylated SEPT9 or methylated SST, which are possible biomarkers of HCC, in combination with AFP may improve clinical performance for the detection of HCC. Study subjects included 25 healthy controls, 15 patients with chronic liver disease without HCC, and 38 patients with HCC. Methylation level of serum cell-free SEPT9 and SST was measured by methylation-sensitive restriction enzymes followed by multiplex droplet digital polymerase chain reaction. According to receiver operating characteristic curve analysis to discriminate between non-HCC group(including control group and chronic liver disease without HCC group)and HCC group, area under the curve(AUC)was 0.73 by AFP and 0.73 by mSEPT9, whereas it was only 0.59 by mSST. Regarding combination tests, although negative predictive values were almost same between the AFP + mSEPT9 test and the AFP + mSST test(75.0% vs 72.2%),a positive predictive value of AFP + mSEPT9 test was higher than that of the AFP + mSST test(79.4% vs. 66.7%).In conclusions, methylated SEPT9 was a better companion marker of AFP for HCC screening than methylated SST.

Effect of photography method and analysis settings in SfM without GCP byusing RTK-UAV : investigation using along-road experiment data

写真測量とリモートセンシング Volume 60 Issue 4

Creators : 高田雅也 | 神野有生 | 加賀谷仁秀 | 春名正基 Date Issued : 2021-09-10

Investigation of the factors of attendance and continuous to participate in dementia café among community-dwelling seniors

山口医学 Volume 70 Issue 2

Creators : Fujimura Kazumi | Hase Ryosuke | Kijima Ayano | Okochi Ayako | Kumagai Tamaki Publishers : 山口大学医学会 Date Issued : 2021-05-13

Sterile inflammation as a novel therapeutic target to heart failure

山口医学 Volume 70 Issue 2

Creators : Suetomi Takeshi Publishers : 山口大学医学会 Date Issued : 2021-05-13

Reports of 2019 fiscal year East Asian project studies