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Prevalence of urinary incontinence and association of vaginal pressure and urinary incontinence in japanese women

山口医学 Volume 64 Issue 2

Creators : Kamezaki Akiko | Tanaka Mayumi Publishers : 山口大学医学会 Date Issued : 2015-05-01

Experiences of middle-aged individuals with a first acute myocardial infarction:a phenomenological study

山口医学 Volume 64 Issue 2

Creators : Kawamura Atsuko | Inagaki Junko Publishers : 山口大学医学会 Date Issued : 2015-05-01

A case of chronic hepatitis c with charcot-marie-tooth disease successfully treated with interferon beta and rivabirin combination therapy

山口医学 Volume 64 Issue 1

A 36-year-old man diagnosed with Charcot-Marie-Tooth(CMT)disease type 1B was treated in the department of neurology of this hospital. Due to a liver injury(AST 237IU/ml, ALT 496IU/ml)which occurred in November 200X, he was introduced to our department. As a result of scrutiny, we diagnosed him with chronic hepatitis C genotype 2a(HCV-RNA 5.4logIU/ml).He will be admitted to the hospital for Interferon(IFN)therapy in April next year. Although the mechanism is unknown, there are a few reports of peripheral neuropathy related to IFN therapy. Therefore, IFN therapy is generally unfavorable for patients with neuromuscular disorders. There are several IFN preparations used in Japan. IFN alfa associated peripheral neuropathy appears less than 0.1-5% of the time. While there is no report of peripheral neuropathy related to IFN beta, we performed IFN beta and Rivabirin combination therapy with a severe follow-up by a neurologist. We could accomplish treatment without the exacerbation of neurologic symptoms. He achieved sustained viral response. When IFN therapy was provided for chronic hepatitis B or chronic hepatitis C complicated with peripheral neuropathy, there is some possibility of performing antiviral therapy safely by using IFN beta.

A case of early gastric cancer that developed 6 years after eradication of helicobacter pylori for nodular gastritis

山口医学 Volume 64 Issue 1

A case of cyclic thrombocytopenia complicated by drug-related damage to the small intestinal mucosa

山口医学 Volume 64 Issue 1

A case of ruptured hepatocellular carcinoma immediately after transcatheter arterial chemoembolization

山口医学 Volume 64 Issue 1

Spontaneous rupture of hepatocellular carcinoma(HCC)is well known. However, rupture of HCC after transcatheter arterial chemoembolization(TACE)is a rare but potentially fatal complication. Herein, we report a case of ruptured HCC after TACE in a 73-year-old man with chronic liver injury(non-B and non-C).He had previously undergone subsegmental resection of S7 of the liver for HCC. One year later, multiple HCCs were detected. TACE was performed for the recurrent HCCs located on the surface of S2 of the liver. Epigastric pain and decreased blood pressure were observed after the treatment. Although his symptoms improved immediately, the patient gradually became anemic. Radiological examination after TACE revealed a hematoma around the S2 lesion. Therefore, we diagnosed rupture of HCC. We performed TAE and could control the bleeding. Few possible mechanisms of ruptured HCC after TACE include increasing pressure inside the tumor and capsular injury due to TACE. Consequently, HCC which has a high risk of rupture after TACE should be assured embolization and careful observation.

Action of sex hormone for proliferative fibrocellular tissue formation in refractory vitreoretinal diseases

山口医学 Volume 64 Issue 1

Creators : Kimura Kazuhiro Publishers : 山口大学医学会 Date Issued : 2015-02-01

Fascinated by plateles

山口医学 Volume 64 Issue 1

Creators : Okano Kozue Publishers : 山口大学医学会 Date Issued : 2015-02-01

ATF1 modulates the heat shock response by regulating the stress-inducible heat shock factor 1 transcription complex

Molecular and cellular biology Volume 35 Issue 1