Experimental studies on Canine Babesiosis : I. Clinical Findings

Clinical and hematological examination on the experimental babesiosis in the dog was done to make clear the nature of an anemic disease in the western distict of Japan. Examination methods were shown in Table 2. The findings were as follows: 1. Four to seven days after the inoculation, the parasites were found in the blood of the dogs and severe anemia and atypical recurrent fever appeared. 2. Splenomegaly was found by palpation. 3. Decrease of RBC was remarkable, and the minimum value was 750,000-2110,000. Hb and PCV decrease paralleled to the decrease of RBC and juvenile erythrocytes and many reticulocytes were found. Many juvenile leukocytes were also appeared and moncytes inereased. 4. Serum protein value was in nomal range, but albumin value was lower and that of globulin was higher than normal, consequently A/G ratio decreased. 5. Inorganic phosphorus value in the serum was suddenly decrease at the severe anemic stage, houwever, potassium value was not decreased remarkably at the same stage. 6. The parasite multiplied by division in the erythrocytes, and its morphological features showed various shapes. Based on these findings, this parasite might be identified as Babesia Gipsoni.