Research on the Test of Hepatic Function with Chromazurol S.　-Report Ⅰ. Mesurements of chromazurols in dog serum.-

A new dye, chromazurol S (CS), was used in nomal and CCL4 injured dogs for evaluating the hepatic functions and the following conclusion was drawn: The CCS concentrations in blood measured at 15 to 30 minutes after an intravenous administration of CS at the level of 10 mg. Per kg, reflected the hepatic functions more sensitively and accurately than other tests, such as fructose tolerance, Tkata-Aratest, BSP test, cholinesterase activity, and urinary urobilinogen. This test has a great practical value in the evaluation of hepatic functions in yhe early stage of liver diseases.