The bulletin of the Yamaguchi Medical School
Continued by：Medical Science & Innovation
EISSN：2758-5441
Back to Top
Permalink : https://petit.lib.yamaguchi-u.ac.jp/1518
The bulletin of the Yamaguchi Medical School Volume 48 Issue 1-2
published_at 2001-06
Nuclear p53 overexpression in pathological T1 bladder cancer : a marker for tumor recurrence and tumor progression
Nuclear p53 overexpression in pathological T1 bladder cancer : a marker for tumor recurrence and tumor progression
About This Article
Descriptions
In order to investigate the malignant potential of stage T1 bladdar tumors the status of p53 overexpression and mucosal change of grossly normal bladder mucosa, respectively, were studied regarding tumor recurrence and tumor progresion. A total of 30 cases with stage T1 bladder tumor were enrolled and selected site mucosal biopsies (SSMB) were taken of randomly selected 17 cases. All cases were treated by transurethral resection and followed for a median period of 39 months. Six of the 30 cases (20%) showed p53 overexpression. Five of the 17 (29%) had mucosal changes (carcinoma in situ
Creator Keywords
p53 overexpression
bladder cancer
mucosal change
tumor recurrence
tumor progression
Other Article