A case of primary hepatic neuroendocrine carcinoma clinically suggested
山口医学 Volume 63 Issue 1
Page 53-60
published_at 2014-02-01
Title
臨床的に肝原発が示唆された神経内分泌癌の一例
A case of primary hepatic neuroendocrine carcinoma clinically suggested
Creators
Urata Yohei
Source Identifiers
Creator Keywords
多血性肝腫瘍
神経内分泌腫瘍
肝原発神経内分泌癌
症例は80歳代男性.左外耳道癌(扁平上皮癌)の精査目的で施行された陽電子放射断層撮影・コンピュータ断層撮影にて肝腫瘍を指摘され,精査加療目的で当科に紹介となった.慢性肝障害を伴わない径20mm大の単発性多血性肝腫瘍であり,血液検査及び画像検査所見からは診断に至らなかったため,経皮的肝腫瘍生検が施行された.免疫組織化学的にChromogranin A・Synaptophysin・CD56はいずれも陽性で,Ki-67 indexが70%であったため,神経内分泌癌(小細胞癌)と確定診断された.同病変に対して肝動脈化学塞栓療法(transcatheter arterial chemoembolization
A hepatic tumor was incidentally detected in an 80-year-old man who was undergoing examination for suspected squamous cell carcinoma of the left external auditory canal with positron emission tomography-computed tomography. Subsequently, the patient was referred to our department for further examination and treatment. The identified hepatic tumor was a 20-mm wide, hypervascular, solitary mass, and no associated chronic liver disorders were observed. Blood tests and imaging studies could not yield an appropriate diagnosis, and therefore, a percutaneous hepatic tumor biopsy was performed. On immunohistochemical staining, positive results were obtained for chromogranin A, synaptophysin, and cluster of differenti-ation 56(CD56),whereas the Ki-67 index was 70%, leading to a definite diagnosis of neuroendocrine carcinoma(small cell carcinoma).Thus, the patient underwent transcatheter arterial chemoembolization(TACE)
Languages
jpn
Resource Type
journal article
Publishers
山口大学医学会
Date Issued
2014-02-01
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools
大学院医学系研究科(医学)