This paper examines : (1) the medical governance of infectious diseases in Taiwan based on the experience of infectious diseases and the background of medical governance reform, (2) the role of big data and digital technology in infectious disease control, (3) medical strategy and non-pharmaceutical intervention, and (4) socio-political viewpoints regarding the COVID-19 pandemic in Taiwan. It will be possible to confirm that Taiwan's non-pharmaceutical intervention strategies, including mask wearing, AHH practices, quarantine / quarantine, travel restrictions and the implementation of social distancing, are increasing the effectiveness of preventive measures during the COVID-19 pandemic. In addition, the combination of extensive risk communication highlighting the importance of early border control, government leadership and preventive action has prevented Taiwan from locking down. These comprehensive preventive measures against COVID-19 in 2020 are more efficient and effective than those implemented during SARS in 2003, as well as immunoassay responses. In addition, democracy provided institutional support for vibrant civil society and synergies between state and civil society, strengthened the legitimacy of Taiwan's crisis governance, and enhanced voluntary compliance among citizens.