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Nuclear p53 overexpression in pathological T1 bladder cancer : a marker for tumor recurrence and tumor progression

The bulletin of the Yamaguchi Medical School Volume 48 Issue 1-2 Page 7-12
published_at 2001-06
A020048000102.pdf
[fulltext] 3.23 MB
Title
Nuclear p53 overexpression in pathological T1 bladder cancer : a marker for tumor recurrence and tumor progression
Creators Tsukamoto Manabu
Creators Oba Kazuo
Creators Yoshihiro Satoru
Creators Matsuyama Hideyasu
Creators Takahashi Mutsuo
Creators Naito Katsusuke
Source Identifiers
Creator Keywords
p53 overexpression bladder cancer mucosal change tumor recurrence tumor progression
In order to investigate the malignant potential of stage T1 bladdar tumors the status of p53 overexpression and mucosal change of grossly normal bladder mucosa, respectively, were studied regarding tumor recurrence and tumor progresion. A total of 30 cases with stage T1 bladder tumor were enrolled and selected site mucosal biopsies (SSMB) were taken of randomly selected 17 cases. All cases were treated by transurethral resection and followed for a median period of 39 months. Six of the 30 cases (20%) showed p53 overexpression. Five of the 17 (29%) had mucosal changes (carcinoma in situ
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 2001-06
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部