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Effect of Indigocarmine Irradiated with Ultraviolet Light on the Mutagenicity of Trp-P-1

Bulletin of the Faculty of Education, Yamaguchi University. Natural science Volume 44 Issue 2 Page 61-67
published_at 1994-10
Title
Effect of Indigocarmine Irradiated with Ultraviolet Light on the Mutagenicity of Trp-P-1
Creators Yamada Jiro
Source Identifiers
Effect of indigocarmine (IC) exposed to ultraviolet light on the mutagenicity of Trp-P-1 was examined. Enhancing effect of IC on the mutagenicity of Trp-P-1 was decreased with elongation of period of ultraviolet irradiation. The enhancing effect of IC was completely removed through the ultraviolet irradiation for 8.5h. Isatin, a derivative of indigoid compound, was also found to increase the reverse mutation induced by Trp-P-1 in the presence of microsomal activation system. Further, the addition of ascorbic acid to the reaction mixture enhanced the mutagenicity of Trp-P-1 by isatin depending on the concentration of ascorbic acid. Conversely, the addition of alph-tocopherol showed no enhancing effect.
Subjects
自然科学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers 山口大学教育学部
Date Issued 1994-10
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1693
[NCID]AN00243950
Schools 教育学部