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Relationship between C-MYC Expression and the Cell Cycle in HL-60 Cells -Flow Cytometric Analysis-

The bulletin of the Yamaguchi Medical School Volume 33 Issue 1 Page 9-12
published_at 1986-12
A020033000102.pdf
[fulltext] 236 KB
Title
Relationship between C-MYC Expression and the Cell Cycle in HL-60 Cells -Flow Cytometric Analysis-
Creators Sasaki Kohsuke
Creators Murakami Tomoyuki
Creators Ogino Tetsuro
Creators Takahashi Manabu
Source Identifiers
Creator Keywords
Oncogene c-myc protein Cell cycle HL-60 Flow cytometry
By flow cytometric measurement of cellular DNA, c-myc protein and cell volume, we attempted to assess the relationship between c-myc gene expression and the cell cycle in exponentially growing human promyrlocytic leukemia cell line (HL-60). The protein product of c-myc gene was stained by an indirect immunofluorescence method using a specific antiserum to human c-myc protein. Bivariate distributions of cellular DNA, the c-myc protein contents and cell volume demonstrated the direct evidence that the c-myc protein increases with the progression of the cell cycle and then is halved by cell division.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 1986-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594273
Schools 医学部